Curriculum Vitae

Jerry W. Curran




Department of Molecular Biophysics and Physiology

Rush University

1750 West Harrison Street

Chicago, Illinois 60612                                 (312)-942-6482



40 E. 9th St. #1217

Chicago, Illinois 60605                                 (312)-913-9980




Birth Date and Place: June 21, 1977, Sandwich, Illinois

Citizenship: United States

Marital Status: Married



Bachelor of Fine Arts from DePaul University, Chicago, Illinois, June 1999



Graduate Student, Rush University Medical Center, Molecular Biophysics and Physiology, 2004-present



            Presidential Scholar, DePaul University 1995-1999

            DePaul University Merit Scholar, 1996-1999

            Dean’s List, 1995-1999; 2003-2004

            Graduated With High Honors, 1999



            Physiology and pharmacology of cellular ion movement and storage

Modification of cellular proteins during heart failure

Excitation-contraction coupling

Ion-motive ATPases

β-Adrenergic Receptor Signaling in Cardiac Myocytes



          Biophysical Society, 2003-present

            American Heart Association, 2005-present





            American Heart Society Scientific Sessions, Dallas, TX, 2005

Annual Meeting of the Biophysical Society, Long Beach, CA, 2005

Annual Meeting of the Biophysical Society, Salt Lake City, UT, 2006

Gordon Conference: Cardiac Regulatory Mech., New London, NH 2006

American Heart Society Scientific Sessions, Chicago, IL, 2006




Ai X, Curran JW, Shannon TR, Bers DM, Pogwizd SM. (2005) Ca2+/Calmodulin-Dependent Protein Kinase Modulates Cardiac Ryanodine Receptor Phosphorylation and Sarcoplasmic Reticulum Ca2+ Leak in Heart Failure. Circ. Res. 97:1314-22.


Curran, J., Hinton, M.J., Rios, E., Bers DM, Shannon TR (2006) Ca-Calmodulin-Dependent Protein Kinase II Increases Sarcoplasmic Reticulum Ca Leak in Rabbits. Circ. Res. (In Press).



Curran, J., Rios, E., Bers, D.M. Shannon, T.R. (2004) Effects of Adrenergic Stimulation Upon Sarcoplasmic Reticulum Ca Leak in Intact Rabbit Ventricular Myocytes. Biophys. J. 86:344a.


Curran, J., Bers, D.M., Shannon, T.R. (2005) Ca-Calmodulin-dependent protein kinase II phosphorylation of the ryanodine receptor increases SR Ca leak.  Biophys. J. 88:487a.


Curran, J., Huke, S., Pogwizd, S., Bers, D.M., Shannon T.R. (2005) Increased Sarcoplasmic Reticulum Calcium Leak in Heart Failure is due to Ca-Calmodulin-dependent Protein Kinase II.  Circulation 112:II277.


Curran, J., Guo, T., Bers, D.M., Shannon, T.R. (2006) Simultaneous Measurements of Free Cytosolic and Free SR [Ca] Using Fura-2 and Fluo-5N to Assess SR Ca Leak in Cardiac Myocytes.  Biophys. J. 90:71a.


Curran, J., Hinton M., Bers, D.M.,, Shannon, T.R. (2007) Isoproterenol Enhances Diastolic Sarcoplasmic Reticulum Ca Leak In Rabbit Ventricular Myocytes in a Ca-Calmodulin-Dependent Protein Kinase II Dependent Manner and PKA-independent Manner.  Biophys. J. (in press).


Curran, J., Hayes Brown, K., Pogwizd S., Bers D.M., Shannon, T.R. (2007) Characterization of ryanodine receptor Ca sensitivity in rabbit ventricular myocytes and propensity for delayed afterdepolarizations.  Biophys. J., (in press).


Santiago, D., Curran J., Lucero, S., Ríos E., Bers, D.M., Lederer, W.J., Stern, M.D., Shannon, T.R. (2007)  Relationship between Ca sparks and SR Ca leak in mouse ventricular myocytes.  Biophys. J. (in press).