Publications, 2009 to date 

     Deconstructing calsequestrin. Complex buffering in the calcium store of skeletal muscle. Royer L, Ríos E. J Physiol.  587:3101-11. 2009.

    Voltage-gated proton channels maintain pH in human neutrophils during phagocytosis.  Morgan D, Capasso M, Musset B, Cherny VV, Ríos E, Dyer MJ, DeCoursey TE. Proc Natl Acad Sci U S A.  106:18022-7. 2009

      Calsequestrin, triadin and more: the molecules that modulate calcium release in cardiac and skeletal muscle. Ríos E, Györke S. J Physiol. 587:3069-70. 2009

      Indo-1 derivatives for local calcium sensing. M. Bannwarth, IR Correa, M Sztretye, S Pouvreau, C Fellay, A Aebischer, L Royer, E Rios, K Johnsson. ACS Chemical Biology 4: 3, 2009.  Cover Article.

      RyR1 Expression and the Cell Boundary TheoremRíos E. J Biol Chem. 285: le13.  2010.     

      Paradoxical buffering of calcium by calsequestrin demonstrated for the calcium store of skeletal muscle.  Royer L, Sztretye M, Manno C, Pouvreau S, Zhou J, Knollmann BC, Protasi F, Allen PD, Ríos E.  J Gen Physiol. 136:325-38.2010 

    The cell boundary theorem: a simple law of the control of cytosolic calcium concentration. Ríos E. J Physiol Sci. 60:81-84. 2010

    Hyperactive intracellular calcium signaling associated with localized mitochondrial defects in skeletal muscle of an animal model of amyotrophic lateral sclerosis. Zhou J, Yi J, Fu R, Liu E, Siddique T, Ríos E, Deng HX. J Biol Chem. 285:705-12. 2010 

     Ca sparks do not explain all ryanodine receptor-mediated SR Ca leak in mouse ventricular myocytes.  Santiago DJ, JW Curran, DM Bers, WJ Lederer, MD Stern, E Ríos, TR Shannon. Biophys J. 98:2111-2120. 2010.

     Hyperactive intracellular calcium signaling associated with localized mitochondrial defects in skeletal muscle of an animal model of amyotrophic lateral sclerosis.  Zhou J, Yi J, Fu R, Liu E, Siddique T, Ríos E, Deng HX.    J. Biol. Chem. 285:705-712. 2010.

     Mitochondrial calcium uptake regulates rapid calcium transients in skeletal muscle during excitation-contraction (E-C) coupling. Yi, J, C Ma, Y Li, N Weisleder, E Ríos, J Ma and J Zhou.   J. Biol. Chem. 286:32436-32443. 2011.

     D4cpv-calsequestrin: a sensitive ratiometric biosensor accurately targeted to the calcium store of skeletal muscle.  Sztretye, M, J Yi, L Figueroa, J Zhou, L Royer and E RíosJ. Gen. Physiol. 138:211-229.  2011. 

     Measurement of RyR permeability reveals a role of calsequestrin in termination of SR Ca2+ release in skeletal muscle.  Sztretye, M, J Yi, L Figueroa, J Zhou, L Royer, P Allen, G Brum and E Ríos .  J. Gen. Physiol. 138:231-247.  2011. 

    Mitochondrial calcium uptake regulates rapid calcium transients in skeletal muscle during excitation-contraction (E-C) coupling. Yi J, Ma C, Li Y, Weisleder N, Ríos E, Ma J, Zhou J.  J Biol Chem.  Sep 16;286(37):32436-43. 2011.

    Properties of Ca2+ sparks revealed by four-dimensional confocal imaging of cardiac muscle. Shkryl, V, Blatter, L and E Rios.  J. Gen. Physiol. 139:189-207  2012.  Cover Article.

    Synthetic localized calcium transients directly probe signaling mechanisms in skeletal muscle.  Figueroa, L, VM Shkryl, J Zhou, C Manno, A Momotake, G Brum , LA Blatter, GCR Ellis-Davies and E Ríos .   .  J. Physiol.  590: 1389-1411. 2012.  Cover Article. 

see also  Waveless mammalian muscle.  Jacquemond V 2012.  J. Physiol 590:1783.

    Altered Ca2+ concentration, permeability and buffering in the myofibre Ca2+ store of a mouse model of malignant hyperthermia. Manno C, Figueroa L, Royer L, Pouvreau S, Lee CS, Volpe P, Nori A, Zhou J, Meissner G, Hamilton SL, Ríos E. J Physiol. 591(Pt 18):4439-57; 2013 .

    Confocal imaging of transmembrane voltage by SEER of di-8-ANEPPS. Manno C, Figueroa L, Fitts R, Ríos E.
J Gen Physiol.  141(3):371-87; 2013.

    Using two dyes with the same fluorophore to monitor cellular calcium concentration in an extended range.
Figueroa L, Shkryl VM, Blatter LA, Ríos E. PLoS One. ;8(2):e55778; 2013.

    Dynamic measurement of the calcium buffering properties of the sarcoplasmic reticulum in mouse skeletal muscle.
Manno C, Sztretye M, Figueroa L, Allen PD, Ríos E. 
J Physiol.  591(Pt 2):423-42.   2013.

    Life and death of a cardiac calcium spark. Stern MD, Ríos E, Maltsev VA. J Gen Physiol.  142(3):257-74. 2013.

    Isoproterenol increases the fraction of spark-dependent RyR-mediated leak in ventricular myocytes. Santiago DJ, Ríos E, Shannon TR. Biophys J.  104(5):976-85. 2013

   El¨"cuplón", unidad funcional del acoplamiento contráctil.  E Rios.  An Facultad Med (Univ. Repúb. Urug.). 2014; 1(1):4-28.  2014.

  A better method to measure total calcium in biological samples yields immediate payoffs. Manno C, Ríos E. J Gen Physiol.  145(3):167-71. 2015.

   The couplonopathies: A comparative approach to a class of diseases of skeletal and cardiac muscle. Ríos E, Figueroa L, Manno C, Kraeva N, Riazi S. 2015. Viewpoint. J Gen Physiol. 2015 Jun;145(6):459-74. doi:0.1085/ jgp.201411321. PMID: 26009541.